structure of 100-00-5

1-Chloro-4-Nitrobenzene

CAS No.: 100-00-5 Brand: MolBest
M. Ft.: C6H4ClNO2 Cat. No: G9835077
M. Wt.: 157.55 MDL: MFCD00007285
Storage: Store in a cool,dry area.
Purity Grade Package Stock Price Quantity
99% RG 25G In Stock 4 USD
99% RG 100G In Stock 6 USD
99% RG 500G In Stock 17 USD
99% RG 2.5KG In Stock 48 USD
99% RG 25KG In Stock 760 USD
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Applications of 100-00-5

1-Chloro-4-nitrobenzene serves as a crucial intermediate in the production of various chemicals:

  • Synthesis of Dyes and Pigments: It is used in manufacturing azo dyes and other colorants.
  • Production of Pharmaceuticals: The compound is involved in synthesizing active pharmaceutical ingredients due to its reactive functional groups.
  • Rubber Industry: It acts as an antioxidant in rubber formulations, improving durability and performance.

Biological Activity of 100-00-5

1-Chloro-4-nitrobenzene exhibits notable biological activity, particularly concerning its toxicity and potential carcinogenic effects. It has been shown to induce methaemoglobin formation and oxidative damage to red blood cells, leading to regenerative anemia in animal studies. In vitro studies indicate that it can induce chromosomal aberrations and sister chromatid exchanges at high doses, suggesting genotoxicity.

The compound is metabolized in mammals primarily through three pathways: reduction of the nitro group, displacement of the chloride ion via glutathione conjugation, and ring hydroxylation. Metabolites such as 4-chloroaniline have been identified as significant products of this metabolism, contributing to its toxicological profile.

NMR spectrum of 100-00-5

Physical sample testing spectrum (NMR) of 100-00-5

Safety Information of 100-00-5

Pictograms

Signal Word

Danger

Hazard Statements

H301 Toxic if swallowed
H311 Toxic in contact with skin
H331 Toxic if inhaled
H341 Suspected of causing genetic defects
H351 Suspected of causing cancer
H373 May causes damage to organs through prolonged or repeated exposure
H411 Toxic to aquatic life with long lasting effects

Safety Data Sheet

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Bulk Packaging Price Explanation of 100-00-5

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Purchase Instructions of 100-00-5

All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

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