structure of 100-33-4

4,4'-(Pentane-1,5-Diylbis(Oxy))Dibenzimidamide

CAS No.: 100-33-4 Brand: MolBest
M. Ft.: C19H24N4O2 Cat. No: G4067243
M. Wt.: 340.42 MDL: No record
Storage: -20°C
Purity Grade Package Stock Price Quantity
98% RG 100MG In Stock 78 USD
98% RG 250MG In Stock 148 USD
98% RG 1G In Stock 401 USD
98% RG 5G In Stock 412 USD
98% RG 25G In Stock 1979 USD
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Applications of 100-33-4

Pentamidine has several clinical applications:

  • Treatment of Pneumocystis pneumonia: Particularly in patients with weakened immune systems, such as those with HIV/AIDS.
  • Management of Leishmaniasis: Used in both cutaneous and visceral forms of the disease.
  • Treatment of Trypanosomiasis: Effective in early stages of African sleeping sickness caused by specific Trypanosoma species.

Additionally, it has been explored for off-label uses in other infections and certain inflammatory conditions due to its immunomodulatory properties.

Biological Activity of 100-33-4

Pentamidine exhibits significant biological activity against various pathogens:

  • Pneumocystis jirovecii: Effective in treating Pneumocystis pneumonia, particularly in immunocompromised patients.
  • Leishmania species: Acts against cutaneous and visceral leishmaniasis caused by these parasites.
  • Trypanosoma species: Specifically targets Trypanosoma brucei gambiense and Trypanosoma brucei rhodesiense, responsible for sleeping sickness.

The drug's efficacy stems from its ability to disrupt multiple cellular pathways within these organisms.

NMR spectrum of 100-33-4

Physical sample testing spectrum (NMR) of 100-33-4

Safety Information of 100-33-4

Pictograms

Signal Word

Warning

Hazard Statements

H302 Harmful if swallowed
H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation

Safety Data Sheet

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Bulk Packaging Price Explanation of 100-33-4

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Purchase Instructions of 100-33-4

All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

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