structure of 1000340-33-9

3,4-Dibromo-7-Azaindole

CAS No.: 1000340-33-9 Brand: MolBest
M. Ft.: C7H4Br2N2 Cat. No: G6534953
M. Wt.: 275.93 MDL: No record
Storage: 2-8°C,Under inert gas.
Purity Grade Package Stock Price Quantity
95% RG 100MG In Stock 10 USD
95% RG 250MG In Stock 23 USD
95% RG 1G In Stock 76 USD
95% RG 5G In Stock 371 USD
95% RG 25G In Stock 1782 USD
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Applications of 1000340-33-9

3,4-Dibromo-7-azaindole has several applications in both research and potential therapeutic contexts:

  • Circadian Rhythm Studies: Its role as a CK1 inhibitor makes it valuable for investigating circadian biology.
  • Pharmaceutical Development: The compound's unique structure may serve as a lead for developing new drugs targeting CK1 or related pathways.
  • Chemical Probes: It can be utilized as a chemical probe in biochemical assays to study protein interactions and signaling pathways.

Biological Activity of 1000340-33-9

Research has shown that 3,4-Dibromo-7-azaindole exhibits significant biological activity, particularly as an inhibitor of casein kinase 1 (CK1). This inhibition modulates circadian rhythms in plants, specifically in Arabidopsis thaliana, by affecting the accumulation of proteins involved in the circadian clock mechanism, such as PRR5 and TOC1. The compound's ability to influence cellular signaling pathways highlights its potential as a tool for studying circadian biology and possibly other cellular processes.

NMR spectrum of 1000340-33-9

Physical sample testing spectrum (NMR) of 1000340-33-9

Safety Information of 1000340-33-9

Pictograms

Signal Word

Warning

Hazard Statements

H302 Harmful if swallowed
H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation

Safety Data Sheet

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