structure of 1000340-34-0

4-Bromo-3-iodo-7-azaindole

CAS No.: 1000340-34-0 Brand: MolBest
M. Ft.: C7H4BrIN2 Cat. No: G6452295
M. Wt.: 322.93 MDL: No record
Storage: 2-8°C
Purity Grade Package Stock Price Quantity
95% RG 100MG In Stock 6 USD
95% RG 250MG In Stock 13 USD
95% RG 1G In Stock 36 USD
95% RG 5G In Stock 172 USD
95% RG 25G In Stock 718 USD
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Applications of 1000340-34-0

4-Bromo-3-iodo-1H-pyrrolo[2,3-b]pyridine serves as a key intermediate in pharmaceutical synthesis. Its unique structure makes it valuable for:

  • Drug Development: It is a building block for synthesizing compounds with potential therapeutic effects against cancer and inflammatory diseases.
  • Imaging Agents: Variants of this compound are being explored as radiolabeled agents for imaging specific receptors in vivo.
  • Research Tools: Its derivatives are utilized in biological studies to elucidate mechanisms involving kinase signaling pathways and other cellular processes.

Biological Activity of 1000340-34-0

Research indicates that compounds containing the pyrrolo[2,3-b]pyridine scaffold exhibit significant biological activities. For instance, derivatives of this compound have shown potential as inhibitors of various kinases, including SGK-1 kinase, which is implicated in several diseases. Additionally, studies have explored its role in modulating phosphodiesterase activity, particularly PDE4B inhibitors that exhibit anti-inflammatory properties. The biological evaluation of related compounds suggests that modifications to the core structure can enhance potency and selectivity against specific biological targets.

NMR spectrum of 1000340-34-0

Physical sample testing spectrum (NMR) of 1000340-34-0

Safety Information of 1000340-34-0

Pictograms

Signal Word

Warning

Hazard Statements

H302 Harmful if swallowed
H312 Harmful in contact with skin
H315 Causes skin irritation
H319 Causes serious eye irritation
H332 Harmful if inhaled
H335 May cause respiratory irritation

Safety Data Sheet

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Purchase Instructions of 1000340-34-0

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