6-Bromo-1H-Pyrrolo[3,2-c]Pyridine-3-Carbaldehyde

6-Bromo-1H-pyrrolo[3,2-c]pyridine-3-carbaldehyde has potential applications in various fields:

• Medicinal Chemistry: Due to its biological activity against FGFRs, it may serve as a lead compound for developing new cancer therapeutics.
• Organic Synthesis: Its unique structure allows for further modifications, making it a versatile building block in synthetic chemistry.
• Material Science: Potential applications in developing new materials due to its unique electronic properties .

This compound exhibits significant biological activity, particularly as an inhibitor of fibroblast growth factor receptors (FGFRs). FGFRs are crucial in regulating cell proliferation, differentiation, and survival. In vitro studies have shown that 6-bromo-1H-pyrrolo[3,2-c]pyridine-3-carbaldehyde can inhibit cell proliferation in cancer cell lines, such as breast cancer 4T1 cells, and induce apoptosis through direct interactions with FGFRs .

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