structure of 100079-26-3

1-(3,4,5-Trihydroxyphenyl)-1-Nonanone

CAS No.: 100079-26-3 Brand: MolBest
M. Ft.: C15H22O4 Cat. No: G7894140
M. Wt.: 266.33 MDL: No record
Storage: 2-8°C,Under inert gas.
Purity Grade Package Stock Price Quantity
98% RG 5MG In Stock 68 USD
98% RG 25MG In Stock 237 USD
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Applications of 100079-26-3

THPN has potential applications in cancer therapy, particularly for melanoma treatment due to its ability to induce autophagic cell death. Its specificity for Nur77 allows for targeted therapeutic strategies that may reduce side effects associated with traditional chemotherapy. Additionally, THPN's role in modulating inflammatory responses suggests potential applications in treating inflammatory diseases. Ongoing research aims to explore its efficacy further and develop derivatives that could enhance its therapeutic profile.

Biological Activity of 100079-26-3

THPN exhibits potent biological activity by specifically targeting Nur77, which plays a crucial role in regulating various cellular functions such as metabolism, inflammation, and apoptosis. In experimental models, THPN has been shown to induce autophagic cell death in melanoma cells by promoting the movement of Nur77 into mitochondria and disrupting mitochondrial functions. This mechanism is significant because it allows THPN to overcome resistance mechanisms present in melanoma cells against conventional apoptosis-inducing drugs. Furthermore, studies indicate that THPN's action can inhibit tumor development and metastasis in vivo, highlighting its potential as an anti-cancer agent.

NMR spectrum of 100079-26-3

Physical sample testing spectrum (NMR) of 100079-26-3

Safety Information of 100079-26-3

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Signal Word

Warning

Hazard Statements

H302 Harmful if swallowed

Safety Data Sheet

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