structure of 100299-08-9

Pemirolast Potassium

CAS No.: 100299-08-9 Brand: MolBest
M. Ft.: C10H7KN6O Cat. No: G9513999
M. Wt.: 266.3 MDL: No record
Storage: 2-8°C,Under inert gas.
Purity Grade Package Stock Price Quantity
98% RG 250MG In Stock 16 USD
98% RG 25G In Stock 451 USD
98% RG 100G In Stock 1715 USD
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Applications of 100299-08-9

Pemirolast potassium is primarily utilized in treating allergic conditions, particularly:

  • Allergic conjunctivitis: Used in ophthalmic formulations to relieve eye itching.
  • Hay fever: Alleviates symptoms associated with seasonal allergies.
  • Pulmonary hypersensitivity: Investigated for its potential use in preventing reactions to certain drugs.

Moreover, its properties as a mast cell stabilizer make it a candidate for further research in managing other allergic and inflammatory conditions .

Biological Activity of 100299-08-9

Pemirolast potassium exhibits notable biological activity as an antihistamine. Its primary mechanism involves binding to histamine H1 receptors, thereby blocking the action of endogenous histamine. This action alleviates symptoms such as itching and redness caused by allergic reactions. Additionally, pemirolast has been shown to inhibit eosinophil chemotaxis into ocular tissues and prevent the release of inflammatory mediators from eosinophils .

The half-life of pemirolast potassium when administered topically is approximately 4.5 hours, indicating its relatively short duration of action .

NMR spectrum of 100299-08-9

Physical sample testing spectrum (NMR) of 100299-08-9

Safety Information of 100299-08-9

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Warning

Hazard Statements

H302 Harmful if swallowed

Safety Data Sheet

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Purchase Instructions of 100299-08-9

All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

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