2-(Methylamino)-1H-Purin-6(7H)-One

N2-Methylguanine has several applications across different fields:

• Biochemistry: Used as a model compound for studying RNA modifications and their effects on translation.
• Genetics: Investigated for its role in mutagenesis and DNA repair mechanisms.
• Pharmaceuticals: Potentially serves as a target for drug development aimed at modulating RNA activity or repairing DNA lesions.

Moreover, N2-methylguanine is recognized as a DNA lesion that can arise from exposure to environmental carcinogens. Its presence can lead to mutagenesis if not properly repaired, as it may mispair during DNA replication. The enzyme O6-methylguanine-DNA methyltransferase is responsible for repairing such lesions, highlighting its significance in maintaining genomic integrity.

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All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

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