structure of 100324-81-0

(R)-1-(5-Hydroxyhexyl)-3,7-Dimethyl-1H-Purine-2,6(3H,7H)-Dione

CAS No.: 100324-81-0 Brand: MolBest
M. Ft.: C13H20N4O3 Cat. No: G7921374
M. Wt.: 280.32 MDL: No record
Storage: -20°C,Under inert gas.
Purity Grade Package Stock Price Quantity
97% RG 100MG In Stock 1310 USD
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Applications of 100324-81-0

(R)-Lisofylline is primarily being researched for its potential applications in:

  • Type 1 Diabetes Treatment: Its ability to prevent diabetes onset in preclinical models positions it as a promising therapeutic agent.
  • Anti-inflammatory Therapy: Given its mechanism of action against inflammatory cytokines, it may also be beneficial in treating other inflammatory conditions.
  • Mitochondrial Function Improvement: Its effects on cellular metabolism could open avenues for treating metabolic disorders associated with diabetes.

Biological Activity of 100324-81-0

The biological activity of (R)-Lisofylline is primarily linked to its anti-inflammatory effects. It has been demonstrated to protect pancreatic β-cells from dysfunction induced by Th1 cytokines, which are often implicated in autoimmune damage associated with Type 1 Diabetes. Additionally, (R)-Lisofylline enhances mitochondrial function in cells and improves the viability of isolated or transplanted pancreatic islets, making it a candidate for diabetes treatment.

NMR spectrum of 100324-81-0

Physical sample testing spectrum (NMR) of 100324-81-0

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Purchase Instructions of 100324-81-0

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