1-Ethyl-1H-Benzo[D]Imidazol-2(3H)-One

1-EBIO has several applications in research and potential therapeutic areas:

• Pharmacological Research: It serves as a tool for studying calcium-activated potassium channels and their physiological roles.
• Epithelial Ion Transport Studies: Its ability to stimulate chloride secretion makes it valuable for investigating conditions like cystic fibrosis or other disorders related to ion transport dysfunction.
• Cancer Research: The protective effects observed in cancer cells highlight its potential role in cancer therapy strategies aimed at modulating ion channel activity.

1-EBIO exhibits various biological activities linked to its role in ion channel modulation. Notably, it has been shown to rescue head and neck squamous cell carcinoma cells from calcium ionophore-induced cell death by activating potassium channels. Additionally, it stimulates chloride secretion in epithelial cells, contributing to its potential therapeutic applications in conditions involving dysregulated ion transport.

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All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

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