O-Acetyl Losartan
| Purity | Grade | Package | Stock | Price | Quantity |
|---|---|---|---|---|---|
| 95% | RG | 100MG | In Stock | 388 USD | |
| 95% | RG | 250MG | In Stock | 754 USD | |
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Applications of 1006062-27-6
O-Acetyl Losartan has potential applications in various fields:
- Pharmaceutical Development: As a lead compound for developing new antihypertensive agents with improved pharmacokinetic profiles.
- Research: Useful in studying the mechanisms of angiotensin II receptor antagonism and its effects on cardiovascular health.
- Drug Formulation: It may be incorporated into combination therapies for enhanced efficacy against hypertension and related disorders.
Biological Activity of 1006062-27-6
O-Acetyl Losartan exhibits biological activities similar to those of Losartan, acting primarily as an antagonist at the angiotensin II type 1 receptor (AT1). This mechanism leads to:
- Vasodilation: By blocking angiotensin II, it promotes relaxation of vascular smooth muscle.
- Antihypertensive Effects: It effectively lowers blood pressure by preventing vasoconstriction.
- Renal Protection: It may offer protective effects on renal function by modulating blood flow and pressure in the kidneys.
The active metabolite of Losartan, E-3174, retains a significant role in mediating these effects, and O-Acetyl Losartan may also be metabolized to this form.
Safety Information of 1006062-27-6
Download COA of 1006062-27-6
Bulk Packaging Price Explanation of 1006062-27-6
Please email your required order quantity and detailed technical specifications to sales@.
Our sales team will promptly prepare an accurate quotation for your bulk order and provide a comprehensive pricing proposal.
Purchase Instructions of 1006062-27-6
All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.
These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.
Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.
New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information. Additional restrictions may apply.
