structure of 1009298-09-2

Azd-8055

CAS No.: 1009298-09-2 Brand: MolBest
M. Ft.: C25H31N5O4 Cat. No: G6147563
M. Wt.: 465.54 MDL: MFCD16660191
Storage: 2-8°C
Purity Grade Package Stock Price Quantity
97% RG 250MG In Stock 223 USD
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Applications of 1009298-09-2

AZD8055 is primarily investigated for its applications in oncology. It has been studied for:

  • Treatment of advanced solid tumors
  • Management of lymphomas
  • Potential use in combination therapies with other anticancer agents

The compound's ability to inhibit both mTORC1 and mTORC2 makes it a valuable candidate for overcoming resistance seen with traditional mTOR inhibitors like rapamycin.

Biological Activity of 1009298-09-2

AZD8055 has shown significant biological activity in preclinical studies. It effectively inhibits tumor growth in various xenograft models, achieving up to 85% tumor growth inhibition at higher doses in vivo. The compound has also demonstrated activity against a range of cancer cell lines in vitro, indicating its broad potential applicability in cancer therapy.

In clinical trials, AZD8055 was found to have an acceptable safety profile, with dose-limiting toxicities primarily involving elevated liver enzymes. The maximum tolerated dose was established at 90 mg administered twice daily.

NMR spectrum of 1009298-09-2

Physical sample testing spectrum (NMR) of 1009298-09-2

Safety Information of 1009298-09-2

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Signal Word

Warning

Hazard Statements

H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation

Safety Data Sheet

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Bulk Packaging Price Explanation of 1009298-09-2

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Purchase Instructions of 1009298-09-2

All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.

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