structure of 1010100-22-7

5-(Aminomethyl)-2-(2,6-Dioxopiperidin-3-Yl)Isoindoline-1,3-Dione Hydrochloride

CAS No.: 1010100-22-7 Brand: MolBest
M. Ft.: C14H14ClN3O4 Cat. No: G8667966
M. Wt.: 323.73 MDL: No record
Storage: Store under inert gas.
Purity Grade Package Stock Price Quantity
97% RG 100MG In Stock 207 USD
97% RG 250MG In Stock 373 USD
97% RG 1G In Stock 929 USD
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Applications of 1010100-22-7

The potential applications of 5-(Aminomethyl)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride are diverse:

  • Pharmaceutical Development: Its role as a cereblon ligand positions it as a promising candidate for drug development targeting various diseases, particularly cancer.
  • Research Tool: The compound can serve as a valuable tool in biochemical research to study protein degradation pathways and their implications in disease mechanisms.
  • Therapeutic Agents: Due to its biological activity, it may be explored as a therapeutic agent in treating conditions linked to protein misfolding or degradation disorders.

Biological Activity of 1010100-22-7

Research indicates that 5-(Aminomethyl)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride exhibits significant biological activity, particularly as a ligand for cereblon—a protein involved in the ubiquitin-proteasome system. This interaction suggests potential applications in targeted protein degradation therapies, akin to those developed for thalidomide derivatives. Additionally, preliminary studies have shown that this compound may have anti-cancer properties, making it a candidate for further investigation in oncology.

NMR spectrum of 1010100-22-7

Physical sample testing spectrum (NMR) of 1010100-22-7

Safety Information of 1010100-22-7

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Signal Word

Warning

Hazard Statements

H302 Harmful if swallowed
H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation

Safety Data Sheet

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