structure of 1013753-99-5

1-(Benzenesulfonyl)-N-[(2S)-1-[(2-Methoxyphenyl)Methylamino]-1-Oxopropan-2-Yl]Piperidine-4-Carboxamide

CAS No.: 1013753-99-5 Brand: MolBest
M. Ft.: C23H29N3O5S Cat. No: G5215084
M. Wt.: 459.6 MDL: No record
Storage: No record
Purity Grade Package Stock Price Quantity
99% RG 1G In Stock 579 USD
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Applications of 1013753-99-5

BC-1382 has several applications across different fields:

  • Chemistry: It serves as a tool compound for studying the ubiquitin-proteasome system and protein degradation pathways.
  • Biology: Researchers investigate its role in modulating inflammatory responses and cellular signaling pathways.
  • Medicine: There is ongoing exploration into its therapeutic potential for treating inflammatory diseases and certain types of cancer.
  • Industry: The compound is utilized in developing new drugs targeting the ubiquitin-proteasome system.

Biological Activity of 1013753-99-5

BC-1382 exhibits significant biological activity primarily through its inhibition of HECTD2. By disrupting the HECTD2/PIAS1 interaction, it influences several biochemical pathways, notably those involved in inflammation. In laboratory studies, BC-1382 has been shown to reduce proinflammatory cytokine release in human peripheral blood mononuclear cells when stimulated with lipopolysaccharide (LPS). This suggests potential therapeutic applications in inflammatory diseases and conditions driven by excessive cytokine production.

NMR spectrum of 1013753-99-5

Physical sample testing spectrum (NMR) of 1013753-99-5

Safety Information of 1013753-99-5

Pictograms

Signal Word

Warning

Hazard Statements

H302 Harmful if swallowed
H312 Harmful in contact with skin
H315 Causes skin irritation
H319 Causes serious eye irritation
H332 Harmful if inhaled
H335 May cause respiratory irritation

Safety Data Sheet

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Purchase Instructions of 1013753-99-5

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