structure of 1015610-31-7

4-Chloro-5-Iodo-1H-Pyrrolo[2,3-B]Pyridine

CAS No.: 1015610-31-7 Brand: MolBest
M. Ft.: C7H4ClIN2 Cat. No: G7086027
M. Wt.: 278.48 MDL: MFCD09965886
Storage: Store in a cool,dry area.
Purity Grade Package Stock Price Quantity
97% RG 250MG In Stock 12 USD
97% RG 5G In Stock 105 USD
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Applications of 1015610-31-7

4-Chloro-5-iodo-1H-pyrrolo[2,3-b]pyridine has several notable applications:

  • Medicinal Chemistry: As a scaffold for developing FGFR inhibitors, it holds promise for cancer treatment.
  • Chemical Biology: Used in studies aimed at understanding receptor signaling pathways and their implications in disease.
  • Material Science: Potentially utilized in creating novel materials due to its unique electronic properties.

The compound serves as a building block in synthetic organic chemistry, enabling researchers to explore new derivatives with tailored biological activities.

Biological Activity of 1015610-31-7

Research indicates that 4-chloro-5-iodo-1H-pyrrolo[2,3-b]pyridine derivatives exhibit significant biological activity, particularly as inhibitors of fibroblast growth factor receptors (FGFRs). These receptors are implicated in various cancers; thus, targeting them represents a promising strategy for cancer therapy. In vitro studies have shown that certain derivatives possess potent inhibitory effects on FGFR1–4, with IC50 values indicating strong activity against breast cancer cell lines. Additionally, these compounds may exhibit other biological activities that warrant further investigation.

Safety Information of 1015610-31-7

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Signal Word

Warning

Hazard Statements

H302 Harmful if swallowed
H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation

Safety Data Sheet

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Purchase Instructions of 1015610-31-7

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