structure of 10177-15-8

5-Phenylnicotinamide

CAS No.: 10177-15-8 Brand: MolBest
M. Ft.: C12H10N2O Cat. No: G8798656
M. Wt.: 198.22 MDL: No record
Storage: Store in a cool,dry area.
Purity Grade Package Stock Price Quantity
98% RG 100MG In Stock 10 USD
98% RG 1G In Stock 98 USD
98% RG 25G In Stock 2333 USD
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Applications of 10177-15-8

5-Phenylnicotinamide has several applications in medicinal chemistry and pharmacology:

  • Antioxidant Therapy: Due to its ability to modulate NAD+ levels, it may be used in treatments aimed at reducing oxidative stress.
  • Cancer Research: Its derivatives have been explored for anticancer properties, particularly in inhibiting cancer cell proliferation.
  • Pain Management: Compounds related to 5-Phenylnicotinamide have been identified as antagonists for the transient receptor potential vanilloid type 1 channel, which is involved in pain signaling pathways.

Biological Activity of 10177-15-8

The biological activity of 5-Phenylnicotinamide is primarily linked to its role as a precursor in the biosynthesis of nicotinamide adenine dinucleotide (NAD), a crucial coenzyme involved in redox reactions and energy metabolism. It has been shown to exhibit antioxidant properties, potentially restoring cellular NAD+ pools, attenuating oxidative stress, and enhancing cellular metabolism. Additionally, it may influence cell signaling pathways and gene expression, contributing to its therapeutic potential.

NMR spectrum of 10177-15-8

Physical sample testing spectrum (NMR) of 10177-15-8

Safety Information of 10177-15-8

Pictograms

Signal Word

Warning

Hazard Statements

H302 Harmful if swallowed
H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation

Safety Data Sheet

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