structure of 1019206-88-2

Regorafenib (Monohydrate)

CAS No.: 1019206-88-2 Brand: MolBest
M. Ft.: C21H17ClF4N4O4 Cat. No: G5127266
M. Wt.: 500.83 MDL: No record
Storage: Store in a cool,dry area.
Purity Grade Package Stock Price Quantity
98% RG 1G In Stock 16 USD
98% RG 25G In Stock 286 USD
98% RG 100G In Stock 1085 USD
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NMR spectrum of 1019206-88-2

Please note that the batch depicted in the provided NMR spectrum may differ from the actual shipped batch; the NMR spectrum corresponding to the shipped batch will be included with the goods.
Physical sample testing spectrum (NMR) of 1019206-88-2

Safety Information of 1019206-88-2

Pictograms

Signal Word

 Danger

Hazard Statements

 H360Df May damage the unborn child; Suspected of damaging fertility
H360FD May damage fertility; May damage the unborn child
H361fd Suspected of damaging fertility; Suspected of damaging the unborn child
H362 May cause harm to breast-fed children
H372 Causes damage to organs through prolonged or repeated exposure
H373 May causes damage to organs through prolonged or repeated exposure
H400 Very toxic to aquatic life
H410 Very toxic to aquatic life with long lasting effects

Safety Data Sheet

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Applications of 1019206-88-2

Regorafenib monohydrate is primarily used in oncology for:

  • Treatment of metastatic colorectal cancer: It is indicated for patients who have previously received standard therapies.
  • Advanced gastrointestinal stromal tumors: Particularly effective when other treatments have failed.
  • Hepatocellular carcinoma: Approved for use in patients with this liver cancer type since 2017.

Additionally, ongoing research is exploring its potential applications in other malignancies and combinations with other therapeutic agents.

Biological Activity of 1019206-88-2

Regorafenib exhibits significant biological activity through its mechanism as a multi-targeted tyrosine kinase inhibitor. It has been shown to:

  • Induce apoptosis in cancer cells.
  • Inhibit cell proliferation.
  • Reduce metastatic potential in various cancer models, particularly breast cancer.

In clinical settings, regorafenib has demonstrated efficacy in prolonging survival in patients with previously treated metastatic colorectal cancer and other malignancies.

Bulk Packaging Price Explanation of 1019206-88-2

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Purchase Instructions of 1019206-88-2

All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.

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