structure of 1020149-73-8

N-(4-((2-Amino-6-Methylpyrimidin-4-Yl)Amino)Phenyl)-4-(Quinolin-4-Ylamino)Benzamide

CAS No.: 1020149-73-8 Brand: MolBest
M. Ft.: C27H23N7O Cat. No: G7259682
M. Wt.: 461.52 MDL: No record
Storage: Store in a cool,dry area.
Purity Grade Package Stock Price Quantity
98% RG 100MG In Stock 400 USD
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NMR spectrum of 1020149-73-8

Please note that the batch depicted in the provided NMR spectrum may differ from the actual shipped batch; the NMR spectrum corresponding to the shipped batch will be included with the goods.
Physical sample testing spectrum (NMR) of 1020149-73-8

Safety Information of 1020149-73-8

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Warning

Hazard Statements

H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation

Safety Data Sheet

Download COA of 1020149-73-8

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Applications of 1020149-73-8

SGI-1027 is primarily investigated for its potential applications in cancer therapy, particularly for tumors characterized by abnormal DNA methylation patterns. Its ability to reactivate tumor suppressor genes positions it as a candidate for treating various malignancies, including liver cancer and leukemia. Additionally, ongoing research aims to explore its utility in combination therapies with other anticancer agents.

Biological Activity of 1020149-73-8

SGI-1027 exhibits significant biological activity as an anticancer agent. Studies have demonstrated its ability to decrease cell viability in a dose-dependent manner and induce apoptosis in cancer cells. Specifically, it has been effective against human hepatocellular carcinoma cells by inhibiting cell proliferation and reactivating silenced tumor suppressor genes. Furthermore, it shows promise in overcoming the limitations of existing DNMT inhibitors due to its unique structural properties and lower toxicity profile.

Bulk Packaging Price Explanation of 1020149-73-8

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Purchase Instructions of 1020149-73-8

All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

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