3,10,11-Trihydroxy-6H-Dibenzo[B,D]Oxocin-7(8H)-One

Protosappanin A has several potential applications:

• Pharmaceutical Development: Its immunosuppressive properties make it a candidate for organ transplantation therapies.
• Neuroprotection: Its ability to protect neuronal cells suggests potential use in neurodegenerative diseases.
• Bone Health: Given its effects on osteoclastogenesis, it may have applications in treating osteoporosis or other bone-related conditions.

Protosappanin A exhibits a range of biological activities:

• Immunosuppressive Effects: It inhibits the interaction between CD14 and Toll-like receptor 4, leading to reduced oxidative and nitrative stress in microglial cells. This mechanism is significant for neuroprotection and inflammation modulation.
• Osteoclastogenesis Inhibition: Research indicates that protosappanin A suppresses osteoclast differentiation and function, making it a candidate for treating bone-related disorders.
• Neuroprotective Properties: It maintains mitochondrial homeostasis in neurons and promotes autophagy, which is crucial during ischemic conditions.

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Our sales team will promptly prepare an accurate quotation for your bulk order and provide a comprehensive pricing proposal.

All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.

New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information. Additional restrictions may apply.