structure of 1024448-59-6

1-Benzyl-4-(4-Chloro-2-Nitrobenzenesulfonyl)Piperazine

CAS No.: 1024448-59-6 Brand: MolBest
M. Ft.: C17H18ClN3O4S Cat. No: G9282675
M. Wt.: 395.86 MDL: No record
Storage: 2-8°C
Purity Grade Package Stock Price Quantity
99% RG 25MG In Stock 42 USD
99% RG 100MG In Stock 44 USD
99% RG 250MG In Stock 98 USD
99% RG 1G In Stock 324 USD
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NMR spectrum of 1024448-59-6

Please note that the batch depicted in the provided NMR spectrum may differ from the actual shipped batch; the NMR spectrum corresponding to the shipped batch will be included with the goods.
Physical sample testing spectrum (NMR) of 1024448-59-6

Safety Information of 1024448-59-6

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Hazard Statements

 H319 Causes serious eye irritation

Safety Data Sheet

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Applications of 1024448-59-6

RN-1747 is primarily utilized in research settings focused on:

  • Pain Research: Investigating mechanisms of pain and potential therapeutic interventions.
  • Neuroscience: Exploring the role of TRPV4 in neuronal signaling and neuroinflammation.
  • Cardiovascular Studies: Understanding how TRPV4 activation influences vascular function and blood pressure regulation.

Its selective action on TRPV4 makes it a crucial tool for elucidating the physiological roles of this receptor in various biological systems.

Biological Activity of 1024448-59-6

The biological activity of RN-1747 is predominantly linked to its role as an agonist for TRPV4. Activation of this receptor has been associated with several physiological responses, including:

  • Pain Sensation: Modulating pain pathways through calcium signaling.
  • Inflammation: Influencing inflammatory responses in various tissues.
  • Thermoregulation: Participating in temperature sensation and regulation.

Studies have shown that RN-1747 can induce significant calcium influx in cells expressing TRPV4, confirming its role as a potent agonist.

Bulk Packaging Price Explanation of 1024448-59-6

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Purchase Instructions of 1024448-59-6

All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

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