6-[(4-Azido-2-Nitrophenyl)Amino]Hexanoic Acid 2,5-Dioxo-3-Sulfo-1-Pyrrolidinyl Ester

Sulfo-SANPAH is utilized in various applications within biochemical research:

• Protein Crosslinking: It is extensively used to create stable crosslinks between proteins, facilitating studies on protein-protein interactions.
• Cell Surface Labeling: The compound can label proteins on cell surfaces without penetrating cell membranes, enabling the study of extracellular interactions.
• Bioconjugation: It serves as a tool for attaching labels or drugs to biomolecules for therapeutic or diagnostic purposes.

Sulfo-SANPAH has demonstrated significant utility in biological applications, particularly in the context of protein crosslinking. It allows researchers to study protein interactions, localization, and function by creating stable complexes that can be analyzed through various biochemical methods. The compound's ability to form covalent bonds under mild conditions minimizes damage to sensitive biomolecules, making it suitable for use in live-cell studies and other sensitive assays.

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