structure of 1025687-58-4

Sodium (6-((5-Fluoro-2-((3,4,5-Trimethoxyphenyl)Amino)Pyrimidin-4-Yl)Amino)-2,2-Dimethyl-3-Oxo-2,3-Dihydro-4H-Pyrido[3,2-B][1,4]Oxazin-4-Yl)Methyl Phosphate

CAS No.: 1025687-58-4 Brand: MolBest
M. Ft.: C23H24FN6Na2O9P Cat. No: G7554053
M. Wt.: 624.42 MDL: No record
Storage: -20°C
Purity Grade Package Stock Price Quantity
98% RG 100MG In Stock 135 USD
98% RG 250MG In Stock 229 USD
98% RG 1G In Stock 619 USD
98% RG 5G In Stock 1459 USD
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NMR spectrum of 1025687-58-4

Please note that the batch depicted in the provided NMR spectrum may differ from the actual shipped batch; the NMR spectrum corresponding to the shipped batch will be included with the goods.
Physical sample testing spectrum (NMR) of 1025687-58-4

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Applications of 1025687-58-4

Fostamatinib disodium is primarily used for:

  • Chronic Immune Thrombocytopenia: It increases platelet counts by inhibiting pathways that lead to platelet destruction.
  • Rheumatoid Arthritis: It has shown promise in reducing inflammation and joint damage.
  • Acute Respiratory Distress Syndrome: Emerging research suggests it may help modulate immune responses in severe COVID-19 cases.

Biological Activity of 1025687-58-4

The primary mechanism of action of fostamatinib disodium involves the inhibition of Syk kinase, which is pivotal in various immune signaling pathways. By blocking Syk activity, fostamatinib effectively reduces platelet destruction mediated by immune cells in conditions such as chronic immune thrombocytopenia. Additionally, it has shown potential effects on T and B lymphocyte activation and may influence cytokine production.

Fostamatinib's biological activity extends beyond hematological applications; it has demonstrated efficacy in models of asthma and other inflammatory conditions by modulating immune responses and reducing inflammation.

Bulk Packaging Price Explanation of 1025687-58-4

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Purchase Instructions of 1025687-58-4

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