N-[4-[(2-Amino-3-chloropyridin-4-yl)oxy]-3-fluorophenyl]-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide
| Purity | Grade | Package | Stock | Price | Quantity |
|---|---|---|---|---|---|
| 99% | RG | 1MG | In Stock | 12 USD | |
Your region is eligible for ordering. Promotion
NMR spectrum of 1025720-94-8
Safety Information of 1025720-94-8
Download COA of 1025720-94-8
Applications of 1025720-94-8
BMS 777607 has been primarily investigated for its potential use in:
- Cancer Therapy: Targeting MET and RON pathways in solid tumors.
- Research: As a tool compound in studies exploring receptor tyrosine kinase signaling pathways and their roles in cancer progression.
In animal models, BMS 777607 has demonstrated significant antitumor activity without systemic toxicity at therapeutic doses.
Biological Activity of 1025720-94-8
BMS 777607 exhibits various anti-cancer effects, including:
- Induction of Apoptosis: It promotes programmed cell death in cancer cells by inhibiting key signaling pathways.
- Decreased Proliferation: The compound significantly reduces the proliferation rates of various cancer cell lines, including breast cancer and glioma cells.
- Inhibition of Migration: BMS 777607 has shown efficacy in reducing the migratory capabilities of cancer cells, thereby potentially limiting metastasis.
In studies involving breast cancer cell lines such as T-47D and ZR-75-1, BMS 777607 inhibited clonogenic growth in a dose-dependent manner.
Bulk Packaging Price Explanation of 1025720-94-8
Please email your required order quantity and detailed technical specifications to sales@.
Our sales team will promptly prepare an accurate quotation for your bulk order and provide a comprehensive pricing proposal.
Purchase Instructions of 1025720-94-8
All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.
These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.
Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.
New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information. Additional restrictions may apply.
