structure of 1025821-33-3

GSK-626616

CAS No.: 1025821-33-3 Brand: MolBest
M. Ft.: C18H10Cl2N4OS Cat. No: G4486776
M. Wt.: 401.3 MDL: No record
Storage: No record
Purity Grade Package Stock Price Quantity
99% RG 100MG In Stock 1012 USD
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NMR spectrum of 1025821-33-3

Please note that the batch depicted in the provided NMR spectrum may differ from the actual shipped batch; the NMR spectrum corresponding to the shipped batch will be included with the goods.
Physical sample testing spectrum (NMR) of 1025821-33-3

Safety Information of 1025821-33-3

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Hazard Statements

H302 Harmful if swallowed
H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation

Safety Data Sheet

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Applications of 1025821-33-3

GSK-626616 has potential applications in research and therapeutic contexts, particularly concerning its role as a DYRK3 inhibitor. It is being investigated for its effects on cancer cell proliferation and survival due to its modulation of stress granule dynamics. Additionally, GSK-626616 may have implications in treating chemotherapy-induced anemia by protecting hematopoietic cells from stress-induced damage. The compound's ability to selectively inhibit specific kinases also makes it a valuable tool for studying kinase-related signaling pathways.

Biological Activity of 1025821-33-3

The biological activity of GSK-626616 is closely tied to its role as a DYRK3 inhibitor. It has been demonstrated to delay the dissolution of stress granules following oxidative stress exposure in cellular models. This effect is significant because it suggests that GSK-626616 can modulate cellular responses to stress by influencing the dynamics of RNA granules, which are critical for managing mRNA translation during cellular stress. Additionally, it has been implicated in potential therapeutic applications related to cancer and other stress-related conditions due to its ability to regulate kinase activity involved in these processes.

Bulk Packaging Price Explanation of 1025821-33-3

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Purchase Instructions of 1025821-33-3

All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

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