structure of 1026287-65-9

2-Chloro-N-(Thiophen-2-Ylmethyl)Quinazolin-4-Amine

CAS No.: 1026287-65-9 Brand: MolBest
M. Ft.: C13H10ClN3S Cat. No: G3620336
M. Wt.: 275.76 MDL: No record
Storage: Store in a cool,dry area.
Purity Grade Package Stock Price Quantity
95% RG 100MG In Stock 53 USD
95% RG 250MG In Stock 116 USD
95% RG 1G In Stock 232 USD
95% RG 25G In Stock 2535 USD
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NMR spectrum of 1026287-65-9

Please note that the batch depicted in the provided NMR spectrum may differ from the actual shipped batch; the NMR spectrum corresponding to the shipped batch will be included with the goods.
Physical sample testing spectrum (NMR) of 1026287-65-9

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Applications of 1026287-65-9

The unique structure of 2-chloro-N-(thiophen-2-ylmethyl)quinazolin-4-amine makes it suitable for various applications:

  • Pharmaceuticals: It serves as a lead compound in drug discovery for developing kinase inhibitors.
  • Research: Used as a tool compound in studies investigating kinase signaling pathways.
  • Synthetic Intermediates: Acts as an intermediate in synthesizing other biologically active compounds due to its functional groups.

Biological Activity of 1026287-65-9

2-chloro-N-(thiophen-2-ylmethyl)quinazolin-4-amine exhibits significant biological activity, particularly as an inhibitor of various kinases. Research has shown that quinazoline derivatives can inhibit Clk1, Clk2, Clk3, Clk4, and Dyrk1A kinases, which are involved in pre-mRNA splicing and other cellular processes. Such inhibition suggests potential applications in treating diseases associated with dysregulated kinase activity, including cancer.

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Purchase Instructions of 1026287-65-9

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