structure of 1028385-32-1

2-Methyl-2-(4-(3-Methyl-2-Oxo-8-(Quinolin-3-Yl)-2,3-Dihydro-1H-Imidazo[4,5-C]Quinolin-1-Yl)Phenyl)Propanenitrile 4-Methylbenzenesulfonate

CAS No.: 1028385-32-1 Brand: MolBest
M. Ft.: C37H31N5O4S Cat. No: G8630996
M. Wt.: 641.74 MDL: No record
Storage: Store in a cool,dry area.
Purity Grade Package Stock Price Quantity
98% RG 100MG In Stock 70 USD
98% RG 250MG In Stock 132 USD
98% RG 1G In Stock 384 USD
98% RG 5G In Stock 1614 USD
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NMR spectrum of 1028385-32-1

Please note that the batch depicted in the provided NMR spectrum may differ from the actual shipped batch; the NMR spectrum corresponding to the shipped batch will be included with the goods.
Physical sample testing spectrum (NMR) of 1028385-32-1

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Applications of 1028385-32-1

Dactolisib Tosylate has a wide range of applications in scientific research:

  • Cancer Research: Investigated for its potential to inhibit tumor growth and improve chemotherapy efficacy.
  • Cell Signaling Studies: Used to explore the PI3K/mTOR signaling pathway's role in cell growth and survival.
  • Drug Development: Serves as a lead compound for developing new inhibitors targeting the PI3K/mTOR pathway.

The compound's unique mechanism makes it a valuable tool in both basic research and clinical settings.

Biological Activity of 1028385-32-1

Dactolisib Tosylate exhibits significant biological activity through its dual inhibition of PI3K and mTOR. This inhibition leads to:

  • Cell Cycle Arrest: Prevents cancer cells from progressing through the cell cycle.
  • Apoptosis Induction: Triggers programmed cell death in tumor cells, enhancing the efficacy of chemotherapy agents.
  • Tumor Growth Inhibition: Demonstrated potential in reducing tumor size in various cancer models.

The compound is currently under investigation for its therapeutic effects against several cancers, including HER2-positive breast cancer and glioblastoma.

Bulk Packaging Price Explanation of 1028385-32-1

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Purchase Instructions of 1028385-32-1

All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

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