structure of 1047644-62-1

N-((S)-1-Amino-3-(3-Fluorophenyl)Propan-2-Yl)-5-Chloro-4-(4-Chloro-1-Methyl-1H-Pyrazol-5-Yl)Thiophene-2-Carboxamide(CAS 1047644-62-1)

CAS No.: 1047644-62-1 Brand: MolBest
M. Ft.: C18H17Cl2FN4OS Cat. No: G6576110
M. Wt.: 427.32 MDL: No record
Storage: -20°C,Under inert gas. Use: For laboratory research use only
Purity Grade Package Stock Price Quantity
99%
Documents:COANMRSDS
RG 100MG In Stock 355 USD
99%
Documents:COANMRSDS
RG 250MG In Stock 576 USD
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Physical and chemical properties of 1047644-62-1

Acidity coefficient

13.03±0.46(Predicted)

Boiling Point

535.1±50.0 °C(Predicted)

Density

1.49±0.1 g/cm3(Predicted)

Exact Mass

426.04800

LogP

4.98550

Molecular Formula

C18H17Cl2FN4OS

Molecular Weight

427.32300

PSA

101.18000

Storage condition

-20℃

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Spectrums of 1047644-62-1

Attention:
1.The NMR spectrum displayed on the page is a pre-sale reference spectrum and may differ from that of the actual received batch.
2.The accompanying documentation will include the NMR spectrum and purity analysis data for the shipped batch.
Physical sample testing spectrum (NMR) of 1047644-62-1

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Applications of 1047644-62-1

Afuresertib is primarily being investigated for its application in oncology, specifically targeting hematologic malignancies. Clinical trials have focused on its use as a single-agent therapy or in combination with other treatments for conditions such as multiple myeloma and acute lymphoblastic leukemia. Its mechanism of action makes it a candidate for overcoming drug resistance often seen in these cancers by effectively inhibiting the AKT signaling pathway.

Retrosynthesis analysis of 1047644-62-1

  • Route#1

    Cas:1047645-80-6
    Cas:1047644-62-1
  • Route#2

    Cas:1047644-62-1

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