Trimethylsilyl Isocyanate(CAS 1118-02-1)
| Purity | Grade | Package | Stock | Price | Quantity |
| 80% | RG | 1G | In Stock | 3 USD
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| 80% | RG | 5G | In Stock | 6 USD
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| 80% | RG | 25G | In Stock | 24 USD
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| 95% | RG | 1G | In Stock | 4 USD
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| 95% | RG | 5G | In Stock | 7 USD
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| 95% | RG | 25G | In Stock | 29 USD
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| 95% | RG | 100G | In Stock | 110 USD
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| 95% | RG | 500G | In Stock | 526 USD
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| 95% | RG | 2.5KG | In Stock | 2525 USD
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Applications of 1118-02-1
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates Synthesis | Used as a silyl protecting reagent for selective protection of amino groups (e.g., primary and secondary amines) to construct peptide or complex molecular frameworks | Reacted with amine substrates under anhydrous inert atmosphere (e.g., nitrogen or argon) at low temperature (–78 °C to 0 °C) to form N-trimethylsilyl carbamate intermediates, followed by mild deprotection |
| Organic Synthesis | Participates in Staudinger coupling, [2+2] cycloaddition, and other reactions to construct β-lactam or heterocyclic structures | Undergoes electrophilic addition with aldehydes, ketones, or imines under Lewis acid catalysis (e.g., TiCl₄, SnCl₄), or cooperates with phosphine reagents to enable aziridine ring-opening/ring-closure |
| Materials Science | Used as a precursor to silane coupling agents to improve interfacial compatibility between inorganic fillers (e.g., SiO₂, TiO₂) and organic polymers | Undergoes condensation with surface hydroxyl groups during sol-gel processing to introduce –NCO–Si(CH₃)₃ moieties, followed by crosslinking with polyols to form organic-inorganic hybrid networks |
| Analytical Chemistry | Used as a derivatization reagent to enhance volatility and detection sensitivity of amines and alcohols in GC-MS or LC-MS | Reacted at room temperature for 10–30 minutes in the presence of a catalytic amount of organic base (e.g., triethylamine) to yield volatile silyl carbamate or silyl carbonate derivatives |
Physical and chemical properties of 1118-02-1
Boiling Point |
91.0±0.0 °C at 760 mmHg |
|---|---|
BRN |
1744962 |
Density |
0.9±0.1 g/cm3 |
Exact Mass |
115.045341 |
Flash Point |
5.7±22.6 °C |
Index of Refraction |
1.410 |
LogP |
2.16 |
Melting Point |
-49°C |
Molecular Formula |
C4H9NOSi |
Molecular Weight |
115.206 |
PSA |
29.43000 |
Sensitivity |
Moisture Sensitive |
Solubility |
Miscible with ethers and o-dichlorobenzene. |
Storage condition |
2-8°C |
Vapour Pressure |
62.1±0.1 mmHg at 25°C |
Spectrums of 1118-02-1
1.The NMR spectrum displayed on the page is a pre-sale reference spectrum and may differ from that of the actual received batch.
2.The accompanying documentation will include the NMR spectrum and purity analysis data for the shipped batch.
Retrosynthesis analysis of 1118-02-1
Cas:13858-09-8
Cas:75-77-4
Cas:1495-51-8
Cas:999-97-3
Cas:13892-06-3
Cas:56924-33-5
Q&A for CAS 1118-02-1
1. How can I verify product quality?
Every batch of our Chemical Reagents is tested to meet ISO 9001 standards. We provide COA & NMR & SDS Provided with each shipment. Batch COA available for verification, and third-party retesting is supported. A full refund is offered if our data is incorrect.
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Orders from Ready stock / In stock items typically Ships Tomorrow via Fast Shipping via FedEx/DHL/UPS. International deliveries usually arrive within 7 business days, subject to customs clearance.
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Hazardous products are labeled and packaged following international regulations. We provide SDS Provided with all hazardous shipments to ensure safe and compliant transport.
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Yes. We support customization of Lab Grade purity, packaging size, and special testing requirements. Share your needs and we’ll provide a tailored solution.
10. Is the COA consistent with the shipped batch?
Yes. Batch COA available matches the actual shipment. COAs shown online are for reference or from previous batches.
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Yes. We offer Lab Supplier services for stable batch consistency, pricing agreements, and safety stock for long-term customers to ensure uninterrupted supply.
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Download SDS of 1118-02-1
Pictograms |
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|---|---|
Signal Word |
Danger |
Hazard Statements |
H225 Highly Flammable liquid and vapor H315 Causes skin irritation H319 Causes serious eye irritation H331 Toxic if inhaled H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled H335 May cause respiratory irritation |
Safety Data Sheet |
Download COA of 1118-02-1
Operate under the ISO 9001 system
