N-(Carbobenzyloxy)-L-Phenylalanine(CAS 1161-13-3)
| Purity | Grade | Package | Stock | Price | Quantity |
| 98% | RG | 25G | In Stock | 5 USD
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| 98% | RG | 100G | In Stock | 14 USD
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| 98% | RG | 500G | In Stock | 42 USD
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| 98% | RG | 2.5KG | In Stock | 186 USD
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| 98% | RG | 10KG | In Stock | 734 USD
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Applications of 1161-13-3
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Amino-protecting group in peptide synthesis | Used as an Nα-protecting group for L-phenylalanine residues in solid-phase peptide synthesis (SPPS); amino groups are reversibly protected with benzyloxycarbonyl (Cbz) and subsequently removed via hydrogenolysis |
| Pharmaceutical Industry | Intermediate for enzyme inhibitors and antitumor agents | Serves as a key chiral building block in the synthesis of active molecules such as angiotensin-converting enzyme (ACE) inhibitors and proteasome inhibitors (e.g., bortezomib analogues) |
| Biochemical Research | Reagent for modifying proteins/peptides in structural and functional studies | Enables selective introduction of the Cbz protecting group in solution-phase or solid-phase systems to investigate amino acid side-chain reactivity, conformational stability, and enzymatic cleavage specificity |
| Organic Synthesis | Chiral auxiliary and asymmetric synthesis building block | Acts as a chiral source in asymmetric alkylation, acylation, and other reactions to construct complex natural products or pharmaceutical molecules containing a phenylalanine backbone |
Physical and chemical properties of 1161-13-3
Acidity coefficient |
3.86±0.10(Predicted) |
|---|---|
Boiling Point |
511.5±50.0 °C at 760 mmHg |
BRN |
2222826 |
Density |
1.2±0.1 g/cm3 |
Exact Mass |
299.115753 |
Flash Point |
263.1±30.1 °C |
Index of Refraction |
1.591 |
LogP |
3.58 |
Melting Point |
85-87 °C(lit.) |
Molecular Formula |
C17H17NO4 |
Molecular Weight |
299.321 |
optical activity |
[α]20/D +5°, c = 5 in acetic acid |
PSA |
75.63000 |
Solubility |
DMF (Sparingly), DMSO (Slightly), Methanol (Slightly) |
Specific rotation |
5 º (c=5,acetic acid) |
Storage condition |
Keep in dark place,Sealed in dry,Room Temperature |
Vapour Pressure |
0.0±1.4 mmHg at 25°C |
Spectrums of 1161-13-3
1.The NMR spectrum displayed on the page is a pre-sale reference spectrum and may differ from that of the actual received batch.
2.The accompanying documentation will include the NMR spectrum and purity analysis data for the shipped batch.
Retrosynthesis analysis of 1161-13-3
Cas:100-51-6
Cas:63-91-2
Q&A for CAS 1161-13-3
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Yes. We support customization of Lab Grade purity, packaging size, and special testing requirements. Share your needs and we’ll provide a tailored solution.
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Yes. Batch COA available matches the actual shipment. COAs shown online are for reference or from previous batches.
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Download SDS of 1161-13-3
Pictograms |
  |
|---|---|
Signal Word |
Danger |
Hazard Statements |
H315 Causes skin irritation H319 Causes serious eye irritation H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled H335 May cause respiratory irritation |
Safety Data Sheet |
Download COA of 1161-13-3
Operate under the ISO 9001 system
