(S)-N1-(2-(Tert-Butyl)-4'-Methyl-[4,5'-Bithiazol]-2'-Yl)Pyrrolidine-1,2-Dicarboxamide(CAS 1166227-08-2)

A66 is primarily researched for its application as a targeted therapy in oncology. Its ability to selectively inhibit p110α makes it a candidate for treating cancers with PIK3CA mutations or high levels of p110α expression. Furthermore, it may have potential applications in other diseases where aberrant phosphoinositide 3-kinase signaling plays a role. The compound is also used in research settings to elucidate the role of p110α in cellular signaling pathways and cancer biology.

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