structure of 1187431-43-1

N-(3-(3-Cyclopropyl-5-((2-Fluoro-4-Iodophenyl)Amino)-6,8-Dimethyl-2,4,7-Trioxo-3,4,6,7-Tetrahydropyrido[4,3-D]Pyrimidin-1(2H)-Yl)Phenyl)Acetamide Dimethyl Sulfoxide Complex(CAS 1187431-43-1)

CAS No.: 1187431-43-1 Brand: MolBest
M. Ft.: C28H29FIN5O5S Cat. No: G9840509
M. Wt.: 693.53 MDL: No record
Storage: 2-8°C,Under inert gas. Use: For laboratory research use only
Purity Grade Package Stock Price Quantity
98%
Documents:COANMRSDS
RG 250MG In Stock 27 USD
98%
Documents:COANMRSDS
RG 1G In Stock 74 USD
98%
Documents:COANMRSDS
RG 5G In Stock 335 USD
98%
Documents:COANMRSDS
RG 25G In Stock 1343 USD
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Applications of 1187431-43-1

Trametinib is primarily indicated for:

  • Treatment of unresectable or metastatic malignant melanoma with BRAF V600E or V600K mutations.
  • Non-small cell lung cancer with similar mutations.
  • Anaplastic thyroid cancer.

It is often used in combination with dabrafenib for enhanced efficacy against tumors harboring BRAF mutations. Additionally, trametinib is being investigated for potential use in other malignancies associated with aberrant MAPK signaling pathways.

Physical and chemical properties of 1187431-43-1

Exact Mass

693.091797

LogP

5.52300

Molecular Formula

C28H29FIN5O5S

Molecular Weight

693.528

PSA

146.90000

Storage condition

2-8℃

Spectrums of 1187431-43-1

Attention:
1.The NMR spectrum displayed on the page is a pre-sale reference spectrum and may differ from that of the actual received batch.
2.The accompanying documentation will include the NMR spectrum and purity analysis data for the shipped batch.
Physical sample testing spectrum (NMR) of 1187431-43-1

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Download SDS of 1187431-43-1

Pictograms

Signal Word

Danger

Hazard Statements

H317 May cause an allergic skin reaction
H361 Suspected of damaging fertility or the unborn child
H361d Suspected of damaging the unborn child
H372 Causes damage to organs through prolonged or repeated exposure
H400 Very toxic to aquatic life
H410 Very toxic to aquatic life with long lasting effects

Safety Data Sheet

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Operate under the ISO 9001 system