N-(3-(5-(2-Aminopyrimidin-4-Yl)-2-(Tert-Butyl)Thiazol-4-Yl)-2-Fluorophenyl)-2,6-Difluorobenzenesulfonamide(CAS 1195765-45-7)
| Purity | Grade | Package | Stock | Price | Quantity |
| 98% | RG | 100MG | In Stock | 19 USD
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| 98% | RG | 250MG | In Stock | 34 USD
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| 98% | RG | 1G | In Stock | 85 USD
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| 98% | RG | 5G | In Stock | 322 USD
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| 98% | RG | 25G | In Stock | 1636 USD
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Your region is eligible for ordering. Available NMR Spectrum
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Applications of 1195765-45-7
Dabrafenib is primarily applied in oncology:
- Melanoma: Used for unresectable or metastatic melanoma with BRAF V600 mutations.
- Non-Small Cell Lung Cancer: Effective in treating advanced non-small cell lung cancer with BRAF mutations.
- Thyroid Cancer: Utilized for anaplastic thyroid cancer that has progressed after other treatments.
- Combination Therapy: Often administered alongside trametinib to enhance treatment outcomes and manage resistance mechanisms.
Physical and chemical properties of 1195765-45-7
Acidity coefficient |
6.62±0.10(Predicted) |
|---|---|
Boiling Point |
653.7±65.0 °C at 760 mmHg |
Density |
1.4±0.1 g/cm3 |
Exact Mass |
519.101074 |
Flash Point |
349.2±34.3 °C |
Index of Refraction |
1.626 |
LogP |
3.54 |
Melting Point |
214-216oC |
Molecular Formula |
C23H20F3N5O2S2 |
Molecular Weight |
519.562 |
PSA |
148.21000 |
Solubility |
very slightly soluble at pH 1 |
Stability |
Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months. |
Storage condition |
-20°C |
Vapour Pressure |
0.0±2.0 mmHg at 25°C |
Spectrums of 1195765-45-7
1.The NMR spectrum displayed on the page is a pre-sale reference spectrum and may differ from that of the actual received batch.
2.The accompanying documentation will include the NMR spectrum and purity analysis data for the shipped batch.
Retrosynthesis analysis of 1195765-45-7
Cas:1195768-23-0
Cas:1195768-20-7
Cas:1195768-19-4
Q&A for CAS 1195765-45-7
1. How can I verify product quality?
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Hazardous products are labeled and packaged following international regulations. We provide SDS Provided with all hazardous shipments to ensure safe and compliant transport.
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Yes. We support customization of Lab Grade purity, packaging size, and special testing requirements. Share your needs and we’ll provide a tailored solution.
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Yes. Batch COA available matches the actual shipment. COAs shown online are for reference or from previous batches.
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Download SDS of 1195765-45-7
Pictograms |
  |
|---|---|
Signal Word |
Warning |
Hazard Statements |
H361 Suspected of damaging fertility or the unborn child H361fd Suspected of damaging fertility; Suspected of damaging the unborn child H373 May causes damage to organs through prolonged or repeated exposure H400 Very toxic to aquatic life H410 Very toxic to aquatic life with long lasting effects H411 Toxic to aquatic life with long lasting effects |
Safety Data Sheet |
Download COA of 1195765-45-7
Operate under the ISO 9001 system
