2-Amino-5-Nitrothiazole(CAS 121-66-4)
| Purity | Grade | Package | Stock | Price | Quantity |
| 98% | RG | 25G | In Stock | 4 USD
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| 98% | RG | 100G | In Stock | 8 USD
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| 98% | RG | 500G | In Stock | 17 USD
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| 98% | RG | 2.5KG | In Stock | 86 USD
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| 98% | RG | 10KG | In Stock | 341 USD
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Applications of 121-66-4
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Key intermediate in the synthesis of sulfonamide antibacterial agents (e.g., sulfathiazole) | Serves as the core scaffold; sulfonamide functionality is introduced via diazotization-coupling or direct condensation with sulfonamide precursors |
| Pharmaceutical Industry | Intermediate in the synthesis of antitubercular and antithyroid drugs | The amino group on the thiazole ring undergoes acylation or alkylation to construct the drug molecule backbone |
| Dye Industry | Intermediate in the synthesis of azo and sulfur dyes | The amino group is diazotized to form a diazonium salt, followed by coupling with aromatic amines or phenols to produce azo dyes |
| Agrochemical Industry | Raw material for synthesizing fungicides and agrochemical derivatives | Chemical modification of the amino group or condensation with organophosphorus or heterocyclic compounds yields fungicidally active agrochemical molecules |
| Chemical R&D | Organic synthesis reagent and building block for novel heterocyclic compounds | Functions as a nitro-substituted thiazole scaffold, participating in reduction and nucleophilic substitution reactions to generate precursors for functional materials |
Physical and chemical properties of 121-66-4
Acidity coefficient |
1.26±0.10(Predicted) |
|---|---|
Boiling Point |
345.1±15.0 °C at 760 mmHg |
BRN |
126797 |
carcinogen classification |
3 (Vol. 31, Sup 7) 1987 |
Decomposition |
When heated to decomposition it emits very toxic fumes of /nitroxides and sulfuric acid/. |
Density |
1.7±0.1 g/cm3 |
Exact Mass |
144.994598 |
Flash Point |
162.5±20.4 °C |
Index of Refraction |
1.705 |
LogP |
log Kow = 0.83 |
Melting Point |
202 °C (decomposes) |
Merck |
14,457 |
Molecular Formula |
C3H3N3O2S |
Molecular Weight |
145.140 |
PSA |
112.97000 |
Sensitivity |
Light Sensitive |
Solubility |
In water, 6.34X10+3 mg/L at 25 °C (est) |
Stability |
Stable. Incompatible with strong acids, strong oxidizing agents, acid chlorides, acid anhydrides. |
Storage condition |
Keep in dark place,Inert atmosphere,2-8°C |
Vapour Pressure |
5.0X10-5 mm Hg at 25 °C (est) |
Water Solubility |
<0.1 g/100 mL at 20 ºC |
Spectrums of 121-66-4
1.The NMR spectrum displayed on the page is a pre-sale reference spectrum and may differ from that of the actual received batch.
2.The accompanying documentation will include the NMR spectrum and purity analysis data for the shipped batch.
Retrosynthesis analysis of 121-66-4
Cas:140-40-9
Cas:59024-01-0
Cas:96-50-4
Q&A for CAS 121-66-4
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Download SDS of 121-66-4
Pictograms |
  |
|---|---|
Signal Word |
Warning |
Hazard Statements |
H302 Harmful if swallowed H315 Causes skin irritation H319 Causes serious eye irritation H335 May cause respiratory irritation H351 Suspected of causing cancer |
Safety Data Sheet |
Download COA of 121-66-4
Operate under the ISO 9001 system
