6-Ethyl-3-((3-Methoxy-4-(4-(4-Methylpiperazin-1-Yl)Piperidin-1-Yl)Phenyl)Amino)-5-((Tetrahydro-2H-Pyran-4-Yl)Amino)Pyrazine-2-Carboxamide(CAS 1254053-43-4)
| Purity | Grade | Package | Stock | Price | Quantity |
| 98% | RG | 25MG | In Stock | 40 USD
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| 98% | RG | 100MG | In Stock | 60 USD
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| 98% | RG | 250MG | In Stock | 106 USD
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| 98% | RG | 1G | In Stock | 244 USD
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| 98% | RG | 5G | In Stock | 773 USD
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Applications of 1254053-43-4
Gilteritinib is primarily used in oncology as a targeted therapy for patients with relapsed or refractory AML harboring FLT3 mutations. Its use has been associated with improved survival outcomes compared to conventional therapies. Ongoing research is exploring its potential applications in combination therapies with other agents to enhance efficacy and broaden its use in other hematological malignancies or solid tumors.
Physical and chemical properties of 1254053-43-4
Acidity coefficient |
14.39±0.50(Predicted) |
|---|---|
Boiling Point |
696.9±55.0 °C at 760 mmHg |
Density |
1.2±0.1 g/cm3 |
Exact Mass |
552.353638 |
Flash Point |
375.3±31.5 °C |
Index of Refraction |
1.627 |
LogP |
4.35 |
Melting Point |
>157°C (dec.) |
Molecular Formula |
C29H44N8O3 |
Molecular Weight |
552.711 |
PSA |
121.11000 |
Solubility |
<1 mg/mL |
Stability |
Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months. |
Storage condition |
-20℃ |
Vapour Pressure |
0.0±2.2 mmHg at 25°C |
Spectrums of 1254053-43-4
1.The NMR spectrum displayed on the page is a pre-sale reference spectrum and may differ from that of the actual received batch.
2.The accompanying documentation will include the NMR spectrum and purity analysis data for the shipped batch.
Q&A for CAS 1254053-43-4
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Yes. Batch COA available matches the actual shipment. COAs shown online are for reference or from previous batches.
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Download SDS of 1254053-43-4
Pictograms |
 |
|---|---|
Signal Word |
Danger |
Hazard Statements |
H360 May damage fertility or the unborn child H373 May causes damage to organs through prolonged or repeated exposure |
Safety Data Sheet |
Download COA of 1254053-43-4
Operate under the ISO 9001 system
