structure of 130693-82-2

Dorzolomide hydrochloride(CAS 130693-82-2)

CAS No.: 130693-82-2 Brand: MolBest
M. Ft.: C10H17ClN2O4S3 Cat. No: G9689802
M. Wt.: 360.9 MDL: No record
Storage: Store in a dark,dry area. Use: For laboratory research use only
HS CODE: 2935009090
Purity Grade Package Stock Price Quantity
99%
Documents:COANMRHPLCSDS
RG 250MG In Stock 24 USD
99%
Documents:COANMRHPLCSDS
RG 1G In Stock 26 USD
99%
Documents:COANMRHPLCSDS
RG 100MG In Stock 29 USD
99%
Documents:COANMRHPLCSDS
RG 5G In Stock 114 USD
99%
Documents:COANMRHPLCSDS
RG 25G In Stock 547 USD
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Applications of 130693-82-2

Dorzolamide hydrochloride is primarily used in ophthalmology to treat elevated intraocular pressure due to:

  • Open-angle glaucoma
  • Ocular hypertension

It is available as a standalone treatment or in combination with other medications like timolol maleate (as Cosopt) to enhance therapeutic efficacy. The drug's ability to penetrate ocular tissues makes it effective in reducing intraocular pressure while minimizing systemic exposure and side effects.

Physical and chemical properties of 130693-82-2

Boiling Point

575.8ºC at 760 mmHg

BRN

5896026

Density

1.53 g/cm3

Exact Mass

360.00400

Flash Point

302ºC

H Bond Acceptors

5

H Bond Donors

2

LogP

4.66680

Melting Point

283-285ºC

Merck

14,3426

Molecular Formula

C10H17ClN2O4S3

Molecular Weight

360.90100

PSA

151.33000

Solubility

Soluble in water, slightly soluble in methanol, very slightly soluble in anhydrous ethanol.

Specific rotation

D24 -8.34° (c = 1 in methanol)

Storage condition

Refrigerator

Vapour Pressure

2.93E-13mmHg at 25°C

λmax

254nm(CHCl3:MeOH= aq.)(lit.)

Spectrums of 130693-82-2

Attention:
1.The NMR spectrum displayed on the page is a pre-sale reference spectrum and may differ from that of the actual received batch.
2.The accompanying documentation will include the NMR spectrum and purity analysis data for the shipped batch.
Physical sample testing spectrum (NMR) of 130693-82-2

Retrosynthesis analysis of 130693-82-2

  • Route#1

    Cas:120279-96-1
    Cas:130693-82-2
  • Route#2

    Cas:120279-26-7
    Cas:130693-82-2
  • Route#3

    Cas:935289-26-2
    Cas:130693-82-2

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Download SDS of 130693-82-2

Pictograms

Signal Word

Warning

Hazard Statements

H302 Harmful if swallowed
H373 May causes damage to organs through prolonged or repeated exposure

Safety Data Sheet

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