structure of 1334169-90-2

m-PEG8-Mal

CAS No.: 1334169-90-2 Brand: MolBest
M. Ft.: C24H42N2O11 Cat. No: G1164729
M. Wt.: 534.6 MDL: No record
Storage: Store in a cool,dry area.
Purity Grade Package Stock Price Quantity
95% RG 100MG In Stock 127 USD
95% RG 250MG In Stock 289 USD
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Applications of 1334169-90-2

m-PEG8-Mal has a wide range of applications in biochemistry and medicinal chemistry, including:

  • Bioconjugation: It is extensively used in the development of antibody-drug conjugates and other bioconjugates.
  • Targeted Drug Delivery: Enhances the delivery of therapeutics by linking them to targeting moieties.
  • PROTAC Development: Serves as a linker in the synthesis of PROTACs, facilitating targeted protein degradation .
  • Diagnostic

Biological Activity of 1334169-90-2

m-PEG8-Mal exhibits significant biological activity due to its ability to facilitate the delivery of therapeutic agents. By linking drugs to proteins or antibodies through the maleimide-thiol reaction, researchers can improve the pharmacokinetics and therapeutic efficacy of these agents. The PEG component also contributes to reduced immunogenicity and enhanced circulation time in biological systems . This compound is particularly relevant in the development of targeted therapies, such as PROTACs (proteolysis-targeting chimeras), which utilize m-PEG8-Mal as a linker for effective drug delivery .

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Purchase Instructions of 1334169-90-2

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