structure of 1337531-36-8

1-(5-(4-Amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)indolin-1-yl)-2-(3-(trifluoromethyl)phenyl)ethanone(CAS 1337531-36-8)

CAS No.: 1337531-36-8 Brand: MolBest
M. Ft.: C24H20F3N5O Cat. No: G9257964
M. Wt.: 451.44 MDL: No record
Storage: No record Use: For laboratory research use only
Purity Grade Package Stock Price Quantity
99%
Documents:COANMRSDS
RG 5MG In Stock 15 USD
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Applications of 1337531-36-8

GSK2606414 is primarily researched for its applications in cancer therapy, particularly in overcoming drug resistance associated with high ABCG2 expression in tumors. It has also been explored for its potential use in neurodegenerative diseases due to its ability to modulate cellular stress responses. Furthermore, ongoing studies investigate its role in inflammatory conditions by examining its effects on cell death pathways mediated by tumor necrosis factor-alpha (TNF-α).

Physical and chemical properties of 1337531-36-8

Acidity coefficient

5.76±0.30(Predicted)

Boiling Point

720.3±60.0 °C at 760 mmHg

Density

1.4±0.1 g/cm3

Exact Mass

451.161987

Flash Point

389.4±32.9 °C

Index of Refraction

1.668

LogP

4.53

Melting Point

176 - 180°C

Molecular Formula

C24H20F3N5O

Molecular Weight

451.444

PSA

77.04000

Solubility

DMSO (Slightly), Methanol (Slightly)

Storage condition

-20°C

Vapour Pressure

0.0±2.3 mmHg at 25°C

Spectrums of 1337531-36-8

Attention:
1.The NMR spectrum displayed on the page is a pre-sale reference spectrum and may differ from that of the actual received batch.
2.The accompanying documentation will include the NMR spectrum and purity analysis data for the shipped batch.
Physical sample testing spectrum (NMR) of 1337531-36-8

Retrosynthesis analysis of 1337531-36-8


Q&A for CAS 1337531-36-8

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Operate under the ISO 9001 system