1-(4-(4-Amino-1-Isopropyl-1H-Pyrazolo[3,4-D]Pyrimidin-3-Yl)Phenyl)-3-(2-Fluoro-5-(Trifluoromethyl)Phenyl)Urea(CAS 1384071-99-1)

AD80 is primarily investigated for its applications in oncology as a targeted therapy for RET-driven tumors, including certain types of lung and colorectal cancers. Its ability to inhibit multiple kinases makes it suitable for use in combination therapies aimed at overcoming resistance mechanisms in cancer treatment. Additionally, AD80's pharmacokinetic profile suggests favorable absorption and distribution characteristics, enhancing its potential for clinical use .

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