Thieno[2,3-d]pyrimidin-4(3H)one

Thieno[2,3-d]pyrimidin-4(3H)-one has several applications:

• Pharmaceutical Development: Its derivatives are being explored as potential drugs for cancer treatment and other diseases due to their inhibitory effects on critical biological pathways.
• Research Tools: These compounds serve as important tools in biochemical research for studying kinase activity and cellular signaling pathways.

Thieno[2,3-d]pyrimidin-4(3H)-one derivatives exhibit significant biological activities:

• Anticancer properties: Some derivatives have shown potent cytotoxic effects against various cancer cell lines, including breast and lung cancer cells. For instance, specific compounds demonstrated IC50 values as low as 4.1 μM against A459 lung cancer cells.
• Kinase inhibition: Recent discoveries identified these compounds as novel inhibitors of Rho-associated protein kinases (ROCK), which are implicated in cancer metastasis and other diseases.
• Antiviral activity: Certain derivatives have been reported to inhibit hepatitis C virus replication and interact with DNA repair proteins.

Please email your required order quantity and detailed technical specifications to sales@.
Our sales team will promptly prepare an accurate quotation for your bulk order and provide a comprehensive pricing proposal.

All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.

New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information. Additional restrictions may apply.