structure of 14441-90-8

5-Phenylisoxazole-3-Carboxylic Acid

CAS No.: 14441-90-8 Brand: MolBest
M. Ft.: C10H7NO3 Cat. No: G7322648
M. Wt.: 189.17 MDL: MFCD00464221
Storage: Store in a cool,dry area.
Purity Grade Package Stock Price Quantity
98% RG 250MG In Stock 4 USD
98% RG 1G In Stock 7 USD
98% RG 5G In Stock 14 USD
98% RG 100G In Stock 413 USD
98% RG 500G In Stock 2022 USD
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Applications of 14441-90-8

The primary applications of 5-Phenylisoxazole-3-carboxylic acid include:

  • Pharmaceutical Development: As a lead compound for developing xanthine oxidase inhibitors.
  • Research Tools: Used in biochemical assays to study enzyme activity related to purine metabolism.
  • Synthetic Intermediates: Serves as a precursor for synthesizing more complex organic molecules in medicinal chemistry.

Biological Activity of 14441-90-8

5-Phenylisoxazole-3-carboxylic acid and its derivatives have been studied for their potential as xanthine oxidase inhibitors. Xanthine oxidase plays a crucial role in uric acid production, making these compounds relevant in treating conditions like gout. Research indicates that certain derivatives demonstrate significant inhibitory potency in the micromolar/submicromolar range.

Additionally, molecular modeling studies suggest that specific substituents on the phenyl moiety can influence binding affinity and selectivity towards xanthine oxidase, providing insights for further drug design.

NMR spectrum of 14441-90-8

Physical sample testing spectrum (NMR) of 14441-90-8

Safety Information of 14441-90-8

Pictograms

Signal Word

Danger

Hazard Statements

H302 Harmful if swallowed
H315 Causes skin irritation
H317 May cause an allergic skin reaction
H319 Causes serious eye irritation
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335 May cause respiratory irritation

Safety Data Sheet

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Purchase Instructions of 14441-90-8

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