structure of 1449-05-4

18α-Glycyrrhetinic Acid

CAS No.: 1449-05-4 Brand: MolBest
M. Ft.: C30H46O4 Cat. No: G1797910
M. Wt.: 470.68 MDL: No record
Storage: 2-8°C
Purity Grade Package Stock Price Quantity
95% RG 5G In Stock 1983 USD
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Applications of 1449-05-4

18alpha-Glycyrrhetinic acid has numerous applications across different fields:

  • Pharmaceuticals: Due to its anti-inflammatory and antioxidant properties, it is used in formulations aimed at treating chronic inflammatory diseases and conditions associated with oxidative stress.
  • Cosmetics: Its ability to modulate skin inflammation makes it a valuable ingredient in skincare products aimed at reducing redness and irritation.
  • Food Industry: As a natural flavoring agent derived from licorice, it is used in various food products for its sweetening properties without significant caloric content.

Biological Activity of 1449-05-4

The biological activity of 18alpha-Glycyrrhetinic acid is extensive:

  • Anti-inflammatory Effects: It inhibits the expression of inducible nitric oxide synthase and cyclooxygenase-2, both key players in inflammatory processes. Additionally, it suppresses the nuclear factor kappa-light-chain-enhancer of activated B cells signaling pathway, which is crucial for inflammation regulation.
  • Antioxidant Properties: The compound activates the nuclear factor erythroid 2-related factor 2 pathway, enhancing cellular defenses against oxidative stress.
  • Anticancer Activity: Studies have shown that 18alpha-Glycyrrhetinic acid can inhibit the proliferation of various cancer cell lines and induce apoptosis through modulation of multiple signaling pathways.

NMR spectrum of 1449-05-4

Physical sample testing spectrum (NMR) of 1449-05-4

Safety Information of 1449-05-4

Pictograms

Signal Word

Warning

Hazard Statements

H302 Harmful if swallowed

Safety Data Sheet

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Bulk Packaging Price Explanation of 1449-05-4

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Purchase Instructions of 1449-05-4

All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

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