Methyl carbamimidothioate sulfate

The primary applications of 2-Methyl-2-thiopseudourea sulfate include:

• Intermediate in Synthesis: Used in the preparation of various agrochemicals such as fungicides and insecticides.
• Pharmaceutical Research: Investigated for its potential therapeutic effects due to its role as an iNOS inhibitor.
• Chemical Reagent: Employed in laboratory settings for synthesizing other organic compounds.

The biological activity of 2-Methyl-2-thiopseudourea sulfate is significant due to its potent inhibitory effects on nitric oxide synthases. It has shown higher potency compared to other known inhibitors such as N-methyl-L-arginine. Specifically, the inhibition constants (K_i values) for human iNOS, endothelial nitric oxide synthase (eNOS), and neuronal nitric oxide synthase (nNOS) are reported to be 120 nM, 200 nM, and 160 nM, respectively.

This compound's ability to modulate nitric oxide production makes it a candidate for research into therapies for conditions associated with excessive nitric oxide production, such as inflammation and neurodegenerative diseases.

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These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

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