structure of 14631-20-0

N4-Acetylcytosine

CAS No.: 14631-20-0 Brand: MolBest
M. Ft.: C6H7N3O2 Cat. No: G8215871
M. Wt.: 153.14 MDL: MFCD00134466
Storage: Store in a cool,dry area.
Purity Grade Package Stock Price Quantity
98% RG 5G In Stock 4 USD
98% RG 25G In Stock 5 USD
98% RG 100G In Stock 11 USD
98% RG 500G In Stock 32 USD
98% RG 2.5KG In Stock 154 USD
98% RG 10KG In Stock 926 USD
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Applications of 14631-20-0

N4-Acetylcytosine has several notable applications:

  • Research Tool: It serves as a valuable tool for studying RNA modifications and their effects on gene expression.
  • Therapeutic Target: Due to its involvement in disease mechanisms, it presents opportunities for developing new therapeutic strategies targeting RNA modifications.
  • Biomarker Potential: Its levels may serve as biomarkers for early diagnosis and prognosis in cancers.

Biological Activity of 14631-20-0

N4-Acetylcytosine is primarily known for its role in RNA modifications, particularly as a component of messenger RNA, transfer RNA, and ribosomal RNA. The modification is catalyzed by N-acetyltransferase 10 (NAT10), which is pivotal for:

  • Gene Expression Regulation: The presence of N4-acetylcytosine enhances the stability of RNA molecules and influences translation rates depending on its position within the RNA sequence. For instance, it can stabilize coding sequences while potentially inhibiting translation when located in the 5' untranslated region.
  • Disease Association: Research indicates that N4-acetylcytosine modifications are implicated in various diseases, including cancer and neuroinflammatory conditions. Its role in activating inflammatory pathways suggests therapeutic potential.

NMR spectrum of 14631-20-0

Physical sample testing spectrum (NMR) of 14631-20-0

Safety Information of 14631-20-0

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Warning

Hazard Statements

H302 Harmful if swallowed
H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation

Safety Data Sheet

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Purchase Instructions of 14631-20-0

All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

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