(R)-(+)-Propylene Oxide

(R)-(+)-propylene oxide has diverse applications across various industries:

• Polyurethane Production: Approximately two-thirds of global production is utilized for manufacturing polyether polyols used in flexible and rigid polyurethane foams.
• Chemical Intermediates: It serves as a precursor for producing various chemicals including propylene glycol, glycerol, and surfactants.
• Pharmaceuticals and Agrochemicals: The unique chiral properties make it valuable in synthesizing enantiomerically pure compounds for pharmaceuticals.

Biologically, propylene oxide exhibits significant activity. It has been shown to interact with DNA, forming various adducts that can lead to mutagenic effects. Studies indicate that propylene oxide can bind covalently to DNA, resulting in the formation of N-7-(2-hydroxypropyl)guanine and other alkylated nucleosides. This interaction has raised concerns regarding its potential carcinogenicity. Furthermore, propylene oxide is metabolized in vivo via conjugation with glutathione or hydrolysis to propylene glycol, which may mitigate some of its toxic effects.

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All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.

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