Diethyl pyrocarbonate
| Purity | Grade | Package | Stock | Price | Quantity |
|---|---|---|---|---|---|
| 99% | RG | 5G | In Stock | 4 USD | |
| 99% | RG | 100G | In Stock | 27 USD | |
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Should you have any questions, please contact us by Email. |
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Applications of 1609-47-8
Diethyl pyrocarbonate finds extensive applications in biochemistry and molecular biology:
- Inactivation of Ribonucleases: It is primarily used to prepare ribonuclease-free water and buffers essential for RNA work.
- Protein Modification: Researchers use it to study the role of specific amino acids in enzymes by selectively modifying histidine residues.
- Nucleic Acid Research: It serves as a tool for probing the structure of nucleic acids, allowing scientists to investigate the effects of modifications on RNA and DNA stability and function.
Biological Activity of 1609-47-8
The primary biological activity of diethyl pyrocarbonate lies in its role as a non-specific inhibitor of ribonuclease enzymes. By modifying critical amino acids in these enzymes, diethyl pyrocarbonate effectively prevents them from degrading ribonucleic acid molecules. This property is particularly valuable in laboratory settings where maintaining RNA integrity is essential for downstream applications such as reverse transcription polymerase chain reaction and RNA sequencing.
Moreover, diethyl pyrocarbonate has been shown to influence enzyme activity and protein conformation. For example, it can alter the enzymatic activity of certain proteins by modifying histidine residues, which are often crucial for catalytic function.
NMR spectrum of 1609-47-8
Safety Information of 1609-47-8
Download COA of 1609-47-8
Bulk Packaging Price Explanation of 1609-47-8
Please email your required order quantity and detailed technical specifications to sales@.
Our sales team will promptly prepare an accurate quotation for your bulk order and provide a comprehensive pricing proposal.
Purchase Instructions of 1609-47-8
All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.
These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.
Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.
New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information. Additional restrictions may apply.

