5,5'-Dimethyl-2,2'-Dipyridyl

Abametapir is primarily indicated for the topical treatment of head lice infestations. Its unique mechanism allows it to be effective against lice that have developed resistance to other treatments. The application involves a single-use lotion that is left on the scalp for ten minutes before rinsing off.

Adverse effects are generally mild but can include skin irritation, redness, burning sensations, and temporary changes in hair color due to its chelating properties.

Abametapir exhibits significant biological activity as a pediculicide. Its primary mode of action is the inhibition of metalloproteinases involved in the lifecycle of head lice (Pediculus capitis). By disrupting these enzymes, abametapir effectively reduces lice viability, preventing their reproduction and survival.

In vitro studies have indicated that abametapir can inhibit liver enzymes CYP3A4, CYP2B6, and CYP1A2 at high concentrations, which may lead to increased blood levels of co-administered drugs metabolized by these enzymes.

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Our sales team will promptly prepare an accurate quotation for your bulk order and provide a comprehensive pricing proposal.

All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.

New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information. Additional restrictions may apply.