2-Methylquinazolin-4-Ol

The unique properties of 2-Methylquinazolin-4-ol make it suitable for various applications:

• Pharmaceuticals: Due to its enzyme inhibitory activity, it has potential use in developing anti-cancer drugs targeting DNA repair pathways.
• Synthetic Intermediates: It serves as a building block for synthesizing other biologically active compounds and derivatives.

2-Methylquinazolin-4-ol exhibits significant biological activity, primarily as an inhibitor of two key enzymes:

• Poly (ADP-ribose) synthetase: This enzyme plays a crucial role in DNA repair and programmed cell death. Inhibition by 2-Methylquinazolin-4-ol affects cell survival and DNA repair processes.
• Mammalian aspartate transcarbamylase (ATCase): This enzyme is essential for pyrimidine biosynthesis. The compound acts as a competitive inhibitor, disrupting nucleotide synthesis and affecting cellular metabolism.

The inhibition of these enzymes suggests potential applications in cancer therapy and other diseases where DNA repair mechanisms are compromised.

Please email your required order quantity and detailed technical specifications to sales@.
Our sales team will promptly prepare an accurate quotation for your bulk order and provide a comprehensive pricing proposal.

All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.

New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information. Additional restrictions may apply.