structure of 18087-76-8

6-Chloro-3-nitro-imidazo[1,2-b]pyridazine

CAS No.: 18087-76-8 Brand: MolBest
M. Ft.: C6H3ClN4O2 Cat. No: G1356249
M. Wt.: 198.57 MDL: MFCD08276991
Storage: Store in a cool,dry area.
Purity Grade Package Stock Price Quantity
97% RG 250MG In Stock 5 USD
97% RG 1G In Stock 10 USD
97% RG 5G In Stock 25 USD
97% RG 100G In Stock 721 USD
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Applications of 18087-76-8

6-Chloro-3-nitroimidazo[1,2-b]pyridazine has several applications in medicinal chemistry:

  • Antiparasitic Development: It serves as a lead compound for designing new antiparasitic agents targeting diseases like African trypanosomiasis and leishmaniasis.
  • Pharmacological Research: Its unique structure allows researchers to explore various derivatives that may possess improved therapeutic profiles.
  • Biological Studies: The compound is used in studies aimed at understanding its interactions with biological systems and potential mechanisms of action against pathogens.

Biological Activity of 18087-76-8

Research indicates that 6-Chloro-3-nitroimidazo[1,2-b]pyridazine exhibits significant biological activity, particularly against parasitic infections. It has shown efficacy against Trypanosoma brucei brucei, the causative agent of African sleeping sickness. The compound's mechanism involves interference with essential metabolic pathways in the parasite, making it a promising candidate for further development in antiparasitic therapies. Additionally, its scaffold has been utilized to design derivatives with enhanced pharmacological profiles and selectivity against various pathogens.

NMR spectrum of 18087-76-8

Physical sample testing spectrum (NMR) of 18087-76-8

Safety Information of 18087-76-8

Pictograms

Signal Word

Warning

Hazard Statements

H302 Harmful if swallowed
H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation

Safety Data Sheet

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Purchase Instructions of 18087-76-8

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