structure of 1818-28-6

1-(2,4,5-Trimethoxyphenyl)Ethan-1-One

CAS No.: 1818-28-6 Brand: MolBest
M. Ft.: C11H14O4 Cat. No: G9527063
M. Wt.: 210.23 MDL: No record
Storage: Store in a cool,dry area.
Purity Grade Package Stock Price Quantity
97% RG 1G In Stock 16 USD
97% RG 5G In Stock 52 USD
97% RG 100G In Stock 607 USD
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Applications of 1818-28-6

2',4',5'-Trimethoxyacetophenone finds applications across various fields:

  • Pharmaceuticals: Due to its biological activity, it is being investigated for potential therapeutic uses in cancer treatment and other diseases.
  • Chemical Research: It serves as a precursor or intermediate in the synthesis of other chemical compounds.
  • Material Science: Its unique properties may be utilized in developing new materials or coatings.

Biological Activity of 1818-28-6

Research indicates that 2',4',5'-trimethoxyacetophenone exhibits significant biological activity. It has been shown to interact with various molecular targets, including enzymes such as aromatase and topoisomerase-II. Additionally, it may interfere with signaling pathways like VEGF (vascular endothelial growth factor) and JAK/STAT (Janus kinase/signal transducer and activator of transcription) pathways.

Studies suggest that this compound acts as a fast-binding analog of colchicine, competing for the colchicine binding site on tubulin. This interaction disrupts tubulin polymerization, which is essential for microtubule formation and cell division, ultimately leading to mitotic arrest and affecting cell viability.

Safety Information of 1818-28-6

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Hazard Statements

H319 Causes serious eye irritation

Safety Data Sheet

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Bulk Packaging Price Explanation of 1818-28-6

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Purchase Instructions of 1818-28-6

All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

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