structure of 188723-58-2

(5-Chloro-2-Fluorophenyl)Methanol(CAS 188723-58-2)

CAS No.: 188723-58-2 Brand: MolBest
M. Ft.: C7H6ClFO Cat. No: G3597568
M. Wt.: 160.57 MDL: No record
Storage: Store in a cool,dry area. Use: For laboratory research use only
HS CODE: 2906299090
Purity Grade Package Stock Price Quantity
98%
Documents:COASDS
RG 1G In Stock 22 USD
98%
Documents:COASDS
RG 5G In Stock 65 USD
98%
Documents:COASDS
RG 25G In Stock 231 USD
98%
Documents:COASDS
RG 100G In Stock 692 USD
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Applications of 188723-58-2

Industry Application Process
Pharmaceutical Intermediates Key intermediate in the synthesis of the antifungal drug voriconazole Prepared by selective reduction of 5-chloro-2-fluorobenzoic acid or its esters (e.g., methyl ester) under anhydrous conditions, commonly using lithium aluminum hydride (LiAlH₄) or sodium borohydride (NaBH₄) with a catalyst; alternatively obtained via alkaline hydrolysis or silver oxide-catalyzed hydrolysis of 5-chloro-2-fluorobenzyl chloride
Pesticide Intermediates Structural building block for synthesizing novel fluorinated benzyl alcohol-based insecticides and fungicides Serves as a starting material in halogen exchange, nitration, and coupling reactions to construct fluorinated heterocycles or substituted phenyl side chains; frequently employed in lead compound optimization for triazole- and pyrimidine-based pesticide candidates
Organic Synthesis Building block for chloro- and fluoro-substituted benzyl alcohol scaffolds, used in ligand design and functional material molecule synthesis Oxidized to the corresponding aldehyde or carboxylic acid; or subjected to halogenation/sulfonylation followed by Suzuki, Heck, and other cross-coupling reactions; also applied in chiral derivatization to prepare precursors for asymmetric catalysis ligands

Physical and chemical properties of 188723-58-2

Boiling Point

232.9ºC at 760mmHg

Density

1.344g/cm3

Exact Mass

160.00900

Flash Point

94.7ºC

Index of Refraction

1.542

LogP

1.97140

Molecular Formula

C7H6ClFO

Molecular Weight

160.57300

PSA

20.23000

Vapour Pressure

0.0319mmHg at 25°C

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Hazard Statements

H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation

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